Short interspersed repeat sequences (SINEs)
consist of midsize repetitive segments of similar
nucleotide sequences with an average of 300
bp. Their basic structure is a tandem duplication
of CG-rich segments separated by adeninerich
segments. The most frequent SINE
sequences in humans are the Alu family (Alu
sequences). With about 500 000 copies, they
make up about 3–6% of the total genome of
humans. An Alu sequence consists of two 130-
bp tandem duplications with A-rich sections
between them. The 3! side (“right side”) contains
an insertion of 32 bp.
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